| Name |
miR-548c-3p
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
Breast
|
| Experiment Method |
RT-qPCR,Dual luciferase reporter assay,Western blot analysis,Transwell assay,IHC
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
knockdown of HIF1A-AS2 by shRNA (sh-HIF1A-AS2) markedly elevated miR-548c-3p level, and the enhanced miR-548c-3p noticeably suppressed cell proliferation, invasion, and epithelial-mesenchymal transition, and promoted senescence in vitro.
|
| Regulation Gene |
HIF1A-AS2
|
| Year |
2019
|
| Pubmed ID |
30774370
|
| Title |
The inhibitive effect of sh-HIF1A-AS2 on the proliferation, invasion, and pathological damage of breast cancer via targeting miR-548c-3p through regulating HIF-1a/VEGF pathway in vitro and vivo.
|
| Drug |
NA
|
| Disease |
breast cancer
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|