Details
| Name | CDKN2A |
| Type | gene |
| Species | Mus musculus |
| Tissue | pancreatic beta-cell |
| Experiment Method | other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | The p16INK4a tumour suppressor accumulates in many tissues as a function of advancing age. p16INK4a is an effector of senescence and a potent inhibitor of the proliferative kinase Cdk4, which is essential for pancreatic beta-cell proliferation in adult ma |
| Regulation Gene | NA |
| Year | 2006 |
| Pubmed ID | 16957737 |
| Title | p16INK4a induces an age-dependent decline in islet regenerative potential. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |