| Name |
miR-570-3p
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
lung
|
| Experiment Method |
RTqPCR,Luciferase assay,Western blotting,SA-B-galactosidase staining
|
| Up/Down |
Up
|
| Pro/Anti |
Pro
|
| Funtion Description |
MiR-570-3p is induced by oxidative stress in airway epithelial cells through p38 MAP kinase-c-Jun signaling and drives senescence by inhibiting sirtuin-1.
|
| Regulation Gene |
sirtuin-1
|
| Year |
2019
|
| Pubmed ID |
30156909
|
| Title |
MicroRNA-570 is a novel regulator of cellular senescence and inflammaging.
|
| Drug |
H2O2
|
| Disease |
Chronic obstructive pulmonary disease
|
| Environment Factors |
oxidation
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|