A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-584-5p
Type miRNA
Species Homo sapiens
Tissue gastric
Experiment Method qRT-PCR,MiRNA RT-PCR,Western blot,dual luciferase reporter assays,Immunofluorescence microscopy,SA-B-gal staining,IHC
Up/Down Down
Pro/Anti Pro
Funtion Description A series of investigations indicated that miR-584-5p promoted senescence and activated the TGFB signaling pathway by downregulation of WWP1.
Regulation Gene WWP1
Year 2017
Pubmed ID 28431583
Title Overexpression of miR-584-5p inhibits proliferation and induces apoptosis by targeting WW domain-containing E3 ubiquitin protein ligase 1 in gastric cancer.
Drug NA
Disease gastric cancer
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA