A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name miR-84
Type miRNA
Species Caenorhabditis elegans
Tissue NA
Experiment Method qRT-PCR
Up/Down Up
Pro/Anti Pro
Funtion Description While the gonad primarily functions in procreation, it also affects animal lifespan. Here we show that removal of theC. elegansgermline triggers a switch in the regulatory state of the organism to promote longevity, co-opting components involved in larval
Regulation Gene DAF-12
Year 2012
Pubmed ID 23239738
Title A steroid receptor-microRNA switch that regulates lifespan in response to signals from the gonad
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA