| Name |
miR-92a
|
| Type |
miRNA
|
| Species |
Homo sapiens
|
| Tissue |
NA
|
| Experiment Method |
Real-time PCR,MTT,ELISA,Western blot
|
| Up/Down |
Down
|
| Pro/Anti |
Pro
|
| Funtion Description |
MiR-92a is up-regulated in aged vascular endothelium. The inhibition of miR-92a expression can inhibit oxidative stress or inflammation via mediating Nrf2-KEAP1-ARE signal pathway, to inhibit endothelial apoptosis and to facilitate cell proliferation.
|
| Regulation Gene |
NA
|
| Year |
2017
|
| Pubmed ID |
28678311
|
| Title |
Regulation of miR-92a on vascular endothelial aging via mediating Nrf2-KEAP1-ARE signal pathway.
|
| Drug |
NA
|
| Disease |
Alzheimer's disease
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
NA
|
| High-throughput |
NA
|