A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CDKN2A
Type gene
Species Homo sapiens
Tissue Blood DNA
Experiment Method PCR,other
Up/Down NA
Pro/Anti Pro
Funtion Description The p16(INK4a)/ARF/p15(INK4b) genetic region and the senescence machinery are active in physical ageing in heterogeneous human populations. The mechanism involved may be via greater cellular restorative activity and reduced stem cell senescence.
Regulation Gene NA
Year 2007
Pubmed ID 17459456
Title A common variant of the p16(INK4a) genetic region is associated with physical function in older people.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA