A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name A-to-I RNA editing
Type RNA editing
Species Mus musculus
Tissue brain
Experiment Method mmPCR-seq,other
Up/Down Up
Pro/Anti Pro
Funtion Description Adenosine-to-inosine (A-to-I) RNA editing is an epigenetic modification catalyzed by adenosine deaminases acting on RNA (ADARs), and is especially prevalent and accumulate with age in the brain.
Regulation Gene NA
Year 2018
Pubmed ID 29310578
Title A-to-I RNA editing in the rat brain is age-dependent, region-specific and sensitive to environmental stress across generations.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput GSE99214