A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CDKN2A
Type gene
Species Homo sapiens
Tissue NA
Experiment Method qRT-PCR,DNA sequencing,other
Up/Down NA
Pro/Anti Pro
Funtion Description Hutchinson-Gilford progeria syndrome (HGPS) is a rare precocious aging syndrome caused by mutations in LMNA that lead to synthesis of a mutant form of prelamin A, generally called progerin, that cannot be processed to mature lamin A. Most HGPS patients ha
Regulation Gene NA
Year 2007
Pubmed ID 17469202
Title Increased progerin expression associated with unusual LMNA mutations causes severe progeroid syndromes.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant 1
High-throughput NA