A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CDKN2A
Type gene
Species Mus musculus
Tissue MEFs
Experiment Method RT-PCR,other
Up/Down NA
Pro/Anti Pro
Funtion Description The tumour-suppressor pathway formed by the alternative reading frame protein of the Cdkn2a locus (Arf) and by p53 (also called Trp53) plays a central part in the detection and elimination of cellular damage, and this constitutes the basis of its potent c
Regulation Gene NA
Year 2007
Pubmed ID 17637672
Title Delayed ageing through damage protection by the Arf/p53 pathway.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA