Details
| Name | 743GG / 1805TT |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | peripheral blood mononuclear cells |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | The TLR1 genotypes 743AA/1805GG (TLR1neg) are associated with a TLR1 negative phenotype, impaired function and susceptibility to tuberculosis. Carriers of heterozygous 743AG/1805TG and homozygous 743GG/1805TT genotypes (TLR1pos) have a TLR1 positive pheno |
| Regulation Gene | TLR1 |
| Year | 2013 |
| Pubmed ID | 23391127 |
| Title | Effects of human Toll-like receptor 1 polymorphisms on |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | SNP |
| High-throughput | NA |