| Name |
A2 variant
|
| Type |
SNP
|
| Species |
Homo sapiens
|
| Tissue |
prostatic
|
| Experiment Method |
PCR
|
| Up/Down |
NA
|
| Pro/Anti |
Anti
|
| Funtion Description |
The A2 variant of 17alpha-hydroxylase (CYP17) and allele 191 of STRP aromatase (CYP19) showed an opposite effect on age-related prostate hyperplasia: CYP17 being associated with increased risk of prostate enlargement and CYP19 with reduced risk.
|
| Regulation Gene |
CYP17
|
| Year |
2002
|
| Pubmed ID |
12370109
|
| Title |
Impact of constitutional genetic variation in androgen/oestrogen-regulating genes on age-related changes in human prostate.
|
| Drug |
NA
|
| Disease |
benign prostatic hyperplasia
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
SNP
|
| High-throughput |
NA
|