Details
| Name | afo1 |
| Type | SNP |
| Species | Saccharomyces cerevisiae |
| Tissue | NA |
| Experiment Method | other |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Here, we present a new long-lived yeast deletion mutation,afo1 (for aging factor one), that confers a 60% increase in replicative lifespan.A comparison of the single and double mutant strains for afo1 and fob1 shows that the longevity phenotype of afo1 i |
| Regulation Gene | TOR1 |
| Year | 2009 |
| Pubmed ID | 20157544 |
| Title | The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1 |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | somatic mutation |
| High-throughput | NA |