A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name apo E
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method immunoblotting
Up/Down Down
Pro/Anti Pro
Funtion Description The frequency of the epsilon 4 allele of apo E was significantly lower in the nonagenarians than in the middle-aged and young adults (P < 0.05). Also, the frequency of EcoRI allele R- of apo B was low in the nonagenarians, whereas the allele frequency for
Regulation Gene apo E
Year 1994
Pubmed ID 8155090
Title Apolipoprotein E and B polymorphisms--longevity factors assessed in nonagenarians.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA