Details
| Name | APOE |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | blood samples |
| Experiment Method | qPCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | We find that the epsilon 4 allele of APOE, which promotes premature atherosclerosis, is significantly less frequent in centenarians than in controls (p < 0.001), while the frequency of the epsilon 2 allele, associated previously with type III and IV hyper |
| Regulation Gene | APOE |
| Year | 1994 |
| Pubmed ID | 8136829 |
| Title | Genetic associations with human longevity at the APOE and ACE loci |
| Drug | NA |
| Disease | prematureatherosclerosis |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | SNP |
| High-throughput | NA |