A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Arg192
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description We have examined these two aminoacidic changes in 579 people aged 20 to 65 years old, and 308 centenarians. We found that the percentage of carriers of the B allele at codon 192 (B+ individuals) is higher in centenarians than in controls (0.539 vs 0.447),
Regulation Gene PON1
Year 2002
Pubmed ID 12082503
Title Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant NA
High-throughput NA