A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Asp312Asn
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description There was a significant difference between frequencies for XPD-312 Asn/Asn genotype in age related cataracts patients (21.6%) and healthy controls (13.2%; p=0.03, OR=1.97, 95% CI=1.06-3.63). Considering the types of age related cataracts, XPD-312 Asn/Asn
Regulation Gene XPD
Year 2011
Pubmed ID 21245954
Title Polymorphisms in two DNA repair genes (XPD and XRCC1)--association with age related cataracts
Drug NA
Disease age-related cataract
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA