A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name bn119
Type SNP
Species Caenorhabditis elegans
Tissue Caenorhabditis elegans strains
Experiment Method other
Up/Down NA
Pro/Anti Anti
Funtion Description DAF-16 was localized to the nucleus in all four mutants, the life span was extended only in the three mutants except bn116. These results suggest that the defect in germline stem cell proliferation, the presence of normal somatic gonadal tissues, and DAF-
Regulation Gene pab-1
Year 2010
Pubmed ID 20680489
Title Two mutations in pab-1 encoding poly(A)-binding protein show similar defects in germline stem cell proliferation but different longevity in C. elegans.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant snp
High-throughput NA