A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name C-3740A
Type SNP
Species Homo sapiens
Tissue MCF-7 cells
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description Two polymorphisms (A-3826G and C-3740A), falling in the upstream promoter region of UCP1, were analyzed in a sample of 910 subjects from southern Italy (475 women and 435 men; age range 40-109). By analyzing haplotype specific survival functions we found
Regulation Gene UCP1
Year 2011
Pubmed ID 21827845
Title Two variants located in the upstream enhancer region of human UCP1 gene affect gene expression and are correlated with human longevity
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA