A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name C677T
Type SNP
Species Homo sapiens
Tissue NA
Experiment Method Perkin-Elmer/Applied Biosystems 7700 Sequence Detection Systems and TaqMan reagents
Up/Down differential expression
Pro/Anti NA
Funtion Description Our results suggest that age and sex modify the contribution of the MTHFR C677T mutation to fasting tHcy concentrations.
Regulation Gene MTHFR
Year 2003
Pubmed ID 14608052
Title Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA