A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name Cln5
Type SNP
Species Mus musculus
Tissue brain
Experiment Method RT-PCR
Up/Down NA
Pro/Anti Pro
Funtion Description Transcript profiling of the brains of the Cln5-/- mice revealed altered expression in several genes involved in neurodegeneration, as well as in defense and immune response, typical of age-associated changes in the CNS.
Regulation Gene Cln5
Year 2004
Pubmed ID 15459177
Title A mouse model for Finnish variant late infantile neuronal ceroid lipofuscinosis, CLN5, reveals neuropathology associated with early aging.
Drug NA
Disease late infantile neuronal ceroid lipofuscinosis
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA