A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name G3174A
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description These findings confirm the importance of the rs2229765 minor allele as a genetic predisposing factor for longevity in Italy where a sex-specific pattern for IGF-1 attenuation with was found.
Regulation Gene IGF-1R
Year 2009
Pubmed ID 19460140
Title A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: a genetic study and evaluation of circulating IGF-1 from the Treviso Longeva (TRELONG) study
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant snp
High-throughput NA