A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name HLA-DQB1
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down Up
Pro/Anti Anti
Funtion Description DRB1*1401, DQB1*0503, DQA1*0101=0104 and DQA1*05 were significantly increased in the centenarians. The significant increase of HLA-DQB1*0503 and/or DQA1*0101=0104 in the centenarians can be explained by a linkage disequilibrium with DRB1*1401, or vice ver
Regulation Gene HLA-DQ
Year 1997
Pubmed ID 9389323
Title Molecular genetic studies on DNA polymorphism of the HLA class II genes associated with human longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA