Details
| Name | IL-6 |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | blood samples |
| Experiment Method | immunoassay |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We found that the proportion of homozygotes for the G allele at -174 locus decreases in centenarian males, but not in centenarian females. Moreover, we found that, only among males, homozygotes for the G allele at -174 locus have higher IL-6 serum levels |
| Regulation Gene | IL-6 |
| Year | 2001 |
| Pubmed ID | 11500818 |
| Title | A gender--dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | SNP |
| High-throughput | NA |