A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CDKN2A
Type gene
Species Mus musculus
Tissue NA
Experiment Method qRT-PCR,other
Up/Down Up
Pro/Anti Pro
Funtion Description The proteins encoded by the Ink4/Arf locus, p16Ink4a, p19Arf and p15Ink4b are major tumour suppressors that oppose aberrant mitogenic signals. The expression levels of the locus are progressively increased during aging. Increased Ink4/Arf gene dosage resu
Regulation Gene NA
Year 2009
Pubmed ID 19239418
Title Anti-aging activity of the Ink4/Arf locus.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA