Details
| Name | Lys751Gln |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | Blood |
| Experiment Method | other |
| Up/Down | Down |
| Pro/Anti | NA |
| Funtion Description | Aging is associated with progressing genomic instability. The XPD gene encodes a DNA helicase involved in nucleotide excision repair and in transcription. We analyzed the common XPD polymorphisms that were previously shown to affect protein's DNA repair e |
| Regulation Gene | XPD(ERCC2) |
| Year | 2010 |
| Pubmed ID | 19707883 |
| Title | Decreased expression and the Lys751Gln polymorphism of the XPD gene are associated with extreme longevity. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | 1 |
| High-throughput | NA |