A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name OGG1 Cys/Cys
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description The OGG1 Cys/Cys genotype frequency was significantly higher in cataract patients (P = 0.014; odds ratio [OR], 2.06; 95% confidence interval [CI], 1.171-3.624). The OGG1 Ser/Ser genotype (P = 0.003; OR, 0.647; 95% CI, 0.487-0.860) seems to have a protecti
Regulation Gene OGG1
Year 2012
Pubmed ID 22306120
Title Genetic polymorphisms in DNA repair genes OGG1, APE1, XRCC1, and XPD and the risk of age-related cataract
Drug NA
Disease age-related cataract
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA