Details
| Name | p53 |
| Type | SNP |
| Species | Mus musculus |
| Tissue | breast |
| Experiment Method | PCR,other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | In Humans, single nucleotide polymorphism (SNP) with either arginine (R72) or Proline (P72) at codon 72 influences p53 activity; the P72 allele has a weaker P53 activity and function in tumor suppression,and p53 codon 72 SNP directly impacts aging and lo |
| Regulation Gene | NA |
| Year | 2018 |
| Pubmed ID | 29557783 |
| Title | A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models. |
| Drug | NA |
| Disease | breast cancer |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |