Details
| Name | p53 |
| Type | SNP |
| Species | Mus musculus |
| Tissue | primary mouse embryo fibroblasts |
| Experiment Method | Immunoblots |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | To investigate whether p53 is sufficient to induce senescence, we introduced a conditional murine p53 allele (p53(val135)) into p53-null mouse embryonic fibroblasts and examined cell proliferation and senescence in cells expressing p53, oncogenic Ras, or |
| Regulation Gene | p53 |
| Year | 2002 |
| Pubmed ID | 11971980 |
| Title | Oncogenic ras and p53 cooperate to induce cellular senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | SNP |
| High-throughput | NA |