A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rpd3
Type SNP
Species Drosophila melanogaster
Tissue Drosophila strains
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description We found that males heterozygous for either a hypomorphic (partial loss-of-function) or null mutation of rpd3 have life-span extension of 33% and 41 to 47%, respectively (Fig. 1A). Females heterozygous for the hypomorphic allele have a 52% increase in lif
Regulation Gene rpd3
Year 2002
Pubmed ID 12459580
Title Longevity regulation by Drosophila Rpd3 deacetylase and caloric restriction.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA