| Name |
rs1047286
|
| Type |
SNP
|
| Species |
Homo sapiens
|
| Tissue |
peripheral-blood leukocytes
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
The risk alleles in C3 (rs1047286, odds ratio [OR]=2.48, 95% confidence interval [CI]=1.64-3.75, p=1.59E-05; rs2230199, OR=2.15, 95% CI=1.48-3.13, p=6.28E-05)were strongly associated with risk of age-related macular degeneration.
|
| Regulation Gene |
C3
|
| Year |
2014
|
| Pubmed ID |
24453474
|
| Title |
CFH haplotypes and ARMS2, C2, C3, and CFB alleles show association with susceptibility to age-related macular degeneration in Mexicans
|
| Drug |
NA
|
| Disease |
age-related macular degeneration
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
SNP
|
| High-throughput |
NA
|