A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs10490924
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description The AA (homozygote risk) genotype at rs11200638 - HTRA1 promoter SNP (P = 0.001) and GG (homozygote risk) genotype at rs10490924 (A69S) in LOC387715/ARMS2 (P = 0.002) were each significantly associated with poorer VA outcome at 12 months after multiple co
Regulation Gene LOC387715/ARMS2
Year 2013
Pubmed ID 23582991
Title Genetic influences on the outcome of anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration
Drug ranibizumab or bevacizumab
Disease age-related macular degeneration
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA