| Name |
rs11200638
|
| Type |
SNP
|
| Species |
Homo sapiens
|
| Tissue |
blood samples
|
| Experiment Method |
qPCR
|
| Up/Down |
NA
|
| Pro/Anti |
NA
|
| Funtion Description |
The AA (homozygote risk) genotype at rs11200638 - HTRA1 promoter SNP (P = 0.001) and GG (homozygote risk) genotype at rs10490924 (A69S) in LOC387715/ARMS2 (P = 0.002) were each significantly associated with poorer VA outcome at 12 months after multiple co
|
| Regulation Gene |
HTRA1
|
| Year |
2013
|
| Pubmed ID |
23582991
|
| Title |
Genetic influences on the outcome of anti-vascular endothelial growth factor treatment in neovascular age-related macular degeneration
|
| Drug |
ranibizumab or bevacizumab
|
| Disease |
age-related macular degeneration
|
| Environment Factors |
NA
|
| Circulating |
1
|
| Variant |
SNP
|
| High-throughput |
NA
|