Details
| Name | rs11200638 |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | NA |
| Experiment Method | qPCR |
| Up/Down | NA |
| Pro/Anti | Pro |
| Funtion Description | The two SNPs, rs10490924 and rs11200638, are in complete linkage disequilibrium (D'=1). The HTRA1 promoter polymorphism, rs11200639, is a strong candidate with a functional consequence that predisposes Japanese to develop neovascular AMD. |
| Regulation Gene | HTRA1 |
| Year | 2007 |
| Pubmed ID | 17438519 |
| Title | HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration |
| Drug | NA |
| Disease | AMD |
| Environment Factors | NA |
| Circulating | NA |
| Variant | snp |
| High-throughput | NA |