A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs11574311
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti NA
Funtion Description The results show that WRN-rs11574311 was initially associated with age-related cataract in general, cortical, and mixed cataracts (P = 0.003, odds ratio [OR] = 1.49; P = 0.001, OR = 1.68; and P < 0.0001, OR = 2.08), BLM-rs1063147 with nuclear cataract (P
Regulation Gene WRN
Year 2013
Pubmed ID 23322570
Title The associations between single nucleotide polymorphisms of DNA repair genes, DNA damage, and age-related cataract: Jiangsu Eye Study
Drug NA
Disease age-related cataract
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA