A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs12050077
Type SNP
Species Homo sapiens
Tissue serum
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description Offspring of centenarians had higher median serum TSH compared to controls with estimated heritability of 0.33 (P = 0.004). Allele frequency of two SNPs in the promoter/enhancer region of TSHR gene, associated with increased serum TSH, was higher in cente
Regulation Gene TSHR
Year 2009
Pubmed ID 19837933
Title Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA