Details
| Name | c-fos |
| Type | gene |
| Species | Homo sapiens |
| Tissue | human fibroblasts |
| Experiment Method | qPCR |
| Up/Down | Down |
| Pro/Anti | Pro |
| Funtion Description | The earliest and the largest changes in gene expression occurred in c-fos and junB at mid-senescence prior to the first slowing in cell growth rates. The basal level of c-fos mRNA decreased to one-ninth that of the early-passage levels, while junB decline |
| Regulation Gene | NA |
| Year | 1992 |
| Pubmed ID | 1511730 |
| Title | An altered repertoire of fos/jun (AP-1) at the onset of replicative senescence. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | NA |
| High-throughput | NA |