A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs1346044
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description Among the five SNPs tested, only WRN rs1346044 was found to be significantly associated between cases and controls before multiple-testing adjustment. The minor C allele of rs1346044 was associated with age-related cataract with an odds ratio (OR) of 0.66
Regulation Gene WRN
Year 2013
Pubmed ID 23334603
Title Polymorphisms of the WRN gene and DNA damage of peripheral lymphocytes in age-related cataract in a Han Chinese population
Drug NA
Disease age-related cataract
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA