A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs1413711
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Pro
Funtion Description We observed a prevalence of homozygosity (TT genotype) of 18.1% for rs1413711 among age-related macular degeneration cases compared with 5.8% among controls (P<0.002). The ORs for this polymorphism were 3.6 (95%CI 1.6-8.2) for homozygous subjects and 1.5
Regulation Gene VEGF
Year 2012
Pubmed ID 21881842
Title Homozygosity for the +674C>T polymorphism on VEGF gene is associated with age-related macular degeneration in a Brazilian cohort
Drug NA
Disease age-related macular degeneration
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA