Details
| Name | rs1776180 |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | Blood |
| Experiment Method | RT-PCR,other |
| Up/Down | Up |
| Pro/Anti | Pro |
| Funtion Description | We tested 92 non-synonymous SNPs in 49 DNA repair genes for a possible association with longevity in a sample of 395 German centenarians and 411 controls. The obtained association signal in exonuclease 1 (EXO1) was further investigated by fine mapping and |
| Regulation Gene | EXO1 |
| Year | 2009 |
| Pubmed ID | 19698732 |
| Title | A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians. |
| Drug | NA |
| Disease | NA |
| Environment Factors | NA |
| Circulating | NA |
| Variant | SNP |
| High-throughput | NA |