A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs17878362
Type SNP
Species Homo sapiens
Tissue blood samples
Experiment Method qPCR
Up/Down NA
Pro/Anti Anti
Funtion Description Statistical analyses stratified on family structure showed that cancer tended to occur ~15 years later in mutation carriers who also carried the variant alleles of two polymorphisms within predicted G4-forming regions, rs17878362 (TP53 PIN3, 16 bp duplica
Regulation Gene TP53
Year 2014
Pubmed ID 24336192
Title Age at cancer onset in germline TP53 mutation carriers: association with polymorphisms in predicted G-quadruplex structures.
Drug NA
Disease LFS/LFL Brazilian
Environment Factors NA
Circulating 1
Variant SNP
High-throughput NA