| Name |
rs1801270
|
| Type |
SNP
|
| Species |
Homo sapiens
|
| Tissue |
HCT117 colon carcinoma cells,DNA samples from NIA Aging Cell and CORIELL bank
|
| Experiment Method |
PCR,DNA sequencing,other
|
| Up/Down |
Down
|
| Pro/Anti |
NA
|
| Funtion Description |
p21 (CDKN1A) gene, a stress-inducible senescence-associated cell cycle inhibitor, expression of which upregulates genes implicated in several age-related diseases. By sequencing the promoter and exons of p21 in genomic DNA of ten individuals over 90 years
|
| Regulation Gene |
CDKN1A
|
| Year |
2009
|
| Pubmed ID |
20126416
|
| Title |
Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population.
|
| Drug |
NA
|
| Disease |
NA
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
SNP
|
| High-throughput |
NA
|