Details
| Name | rs189037 |
| Type | SNP |
| Species | Homo sapiens |
| Tissue | blood samples |
| Experiment Method | Luciferase reporter assay,qPCR |
| Up/Down | NA |
| Pro/Anti | Anti |
| Funtion Description | Significant association between CT genotype and longevity was observed. Meanwhile, the SNP was able to affect expression of ATM mRNA by differentially binding to AP-2a. The CC genotype strongly bound to AP-2a, and the TT genotype showed less binding affin |
| Regulation Gene | ATM gene |
| Year | 2010 |
| Pubmed ID | 20816691 |
| Title | A functional single nucleotide polymorphism in promoter of ATM is associated with longevity. |
| Drug | NA |
| Disease | ATM |
| Environment Factors | NA |
| Circulating | 1 |
| Variant | snp |
| High-throughput | NA |