| Name |
rs2234759
|
| Type |
SNP
|
| Species |
Homo sapiens
|
| Tissue |
pheochromocytoma cell lines
|
| Experiment Method |
Luciferase assay,qPCR
|
| Up/Down |
Up
|
| Pro/Anti |
Anti
|
| Funtion Description |
We found modest association of the age of onset with two NPY promoter variations and a highly significant association with a NPY2R promoter SNP (rs2234759; p=0.0004). Investigating the functional impact of rs2234759 by luciferase assays revealed that the
|
| Regulation Gene |
NPY2R
|
| Year |
2014
|
| Pubmed ID |
24121255
|
| Title |
Association of age at onset in Huntington disease with functional promoter variations in NPY and NPY2R
|
| Drug |
NA
|
| Disease |
Huntington disease
|
| Environment Factors |
NA
|
| Circulating |
NA
|
| Variant |
SNP
|
| High-throughput |
NA
|