A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs2253217
Type SNP
Species Mus musculus
Tissue liver
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description The SIRT7 SNP rs2253217 is associated with human longevity. Sirtuin 7, located in the nucleolus, binds to multiple nuclear and nucleolar proteins, many involved in regulation of RNA polymerase I transcription, increases resistance to oxidative stress, mai
Regulation Gene NA
Year 2018
Pubmed ID 29300832
Title Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA