A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CHR
Type gene
Species Mus musculus
Tissue NA
Experiment Method qPCR
Up/Down Down
Pro/Anti Pro
Funtion Description Researchers tested whether this insulin sensitivity of the GHR-KO mouse is necessary for its retarded aging by abrogating that sensitivity with a transgenic alteration that improves development and secretory function of pancreatic B-cells by expressing Ig
Regulation Gene NA
Year 2014
Pubmed ID 25244225
Title Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA