A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs275653
Type SNP
Species Homo sapiens
Tissue Blood
Experiment Method PCR,other
Up/Down NA
Pro/Anti NA
Funtion Description AGTR1 was sequenced in 173 Italian centenarians and 376 younger controls. A novel non-synonymous mutation was detected in a centenarian. Two polymorphisms in AGTR1 promoter, rs422858 and rs275653, in complete linkage disequilibrium, were significantly ass
Regulation Gene AGTR1
Year 2013
Pubmed ID 22569962
Title Variations of the angiotensin II type 1 receptor gene are associated with extreme human longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA