A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name CITK
Type gene
Species Mus musculus
Tissue NA
Experiment Method western blot
Up/Down Down
Pro/Anti Anti
Funtion Description In medulloblastoma cell lines DAOY and ONS-76, CITK knockdown increased both cytokinesis failure and DNA damage, impairing proliferation and inducing cell senescence and apoptosis via TP53 or TP73.
Regulation Gene NA
Year 2018
Pubmed ID 29921697
Title Inactivation of Citron Kinase Inhibits Medulloblastoma Progression by Inducing Apoptosis and Cell Senescence.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA