A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs3800231
Type SNP
Species Homo sapiens
Tissue NA
Experiment Method Taqman SNP Genotyping Assays
Up/Down Up
Pro/Anti Pro
Funtion Description The human forkhead box O3A gene (FOXO3A) encodes an evolutionarily conserved key regulator of the insulin-IGF1 signaling pathway that is known to influence metabolism and lifespan in model organisms. A recent study described 3 SNPs in the FOXO3A gene that
Regulation Gene FOXO3
Year 2009
Pubmed ID 19196970
Title Association of FOXO3A variation with human longevity confirmed in German centenarians.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant SNP
High-throughput NA