A Manually Curated Knowledgebase of Aging across a variety of Species

Details


Name rs4746720
Type SNP
Species Mus musculus
Tissue liver
Experiment Method PCR,other
Up/Down Up
Pro/Anti Anti
Funtion Description The SNP in SIRT1 regulate aging-related proteins. Studies suggest that the human SIRT1 function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family.
Regulation Gene NA
Year 2018
Pubmed ID 29300832
Title Analysis of Polymorphisms in 59 Potential Candidate Genes for Association With Human Longevity.
Drug NA
Disease NA
Environment Factors NA
Circulating NA
Variant NA
High-throughput NA